On Demand Webinars
Learn how the immunoSEQ Technology can help you drive your next discovery. Create your free SEQdiscovery account for full access to a growing collection of high-value content, including videos, on-demand webinars, high-impact publications, technotes, and case studies.
COVID-19 T-cell Data: Mapping out SARS-CoV-2 Antigen and T-cell Repertoires
Immune Repertoire Sequencing to Uncover SARS-CoV-2-Specific T-Cell Responses and Dynamics
Research Applications of the immunoSEQ Assay in Mouse Models
Applications of Immunosequencing in Autoimmunity
This webinar describes how researchers have applied the immunoSEQ® Technology in the context of autoimmune research including applications in diseases such as Crohn's disease, multiple sclerosis, psoriasis, narcolepsy, and alopecia, as well as treatment-induced autoimmunity. Learn how immunosequencing can be used to understand autoimmune disease pathology, response to different treatment modalities, and duration of treatment response.
T cells in COVID-19: Decoding the Immune Response with Immunosequencing
T cells play a critical role in the adaptive immune system’s response to any virus, including SARS-CoV-2, circulating in the blood to detect and quickly expanding in response to viral challenge, often before symptoms appear. In this webinar, we will discuss the importance of evaluating the T-cell responses from the onset of COVID-19 symptoms through convalescence and the contribution of memory T cells in maintaining durable immunity to SARS-CoV-2.
SARS-CoV-2-Specific T-Cell Map: From Immunosequencing to Data Analysis
In this webinar, we present an overview of Adaptive Biotechnologies' immunoSEQ® Technology, including our new immunoSEQ® T-MAP™ COVID service, the use of robust statistical analyses for COVID-19 data, and how you can easily use the immunoSEQ Analyzer to analyze and visualize your immunosequencing COVID-19 data and integrate it with the ImmuneCODE™ data to gain meaningful insights.
Applications of Gamma/Delta T cells & B cell IgH Sequencing in COVID-19 Research
The COVID-19 pandemic continues to drive an unprecedented worldwide scientific response as we strive to understand the complex immune response elicited by the novel coronavirus SARS-CoV-2. While significant research has focused on the alpha/beta T-cell and neutralizing antibody response to SARS-CoV-2 infection, less attention has been paid to gamma/delta T cells and the broader B-cell response. A complete understanding of COVID-19 pathophysiology requires exploration of the unique contributions gamma/delta T- and B-cells bring to the adaptive immune response.
Immune Repertoire Sequencing to Uncover SARS-CoV-2-Specific T-Cell Responses & Dynamics
In this webinar, we discuss the role of T cells in response to SARS-CoV-2 infection an early insights from Adaptive Biotechnologies' open-access ImmuneCODE™ COVID-19 database, describe the epidemiology of COVID-19 in a cohort of patient samples from Northern Italy, discuss the presence of public SARS-CoV-2-specific clonotypes in COVID-19 patient samples and controls, and analyze differences in the clonal distribution of SARS-CoV-2-specific T cell clonotypes according to different degrees of disease severity.
T Cells in COVID-19: Decoding the Immune Response with Immunosequencing (FOCIS)
In this webinar, we will discuss the role of T-cells in response to COVID-19 and how understanding this immune response can potentially lead to better detection and treatment of COVID-19. We will introduce our comprehensive open access ImmuneCODE™ database that provides COVID-19 data to accelerate ongoing efforts to develop better diagnostics, vaccines, and therapeutics for COVID-19. We will also provide an overview of the immunoSEQ® T-MAP™ COVID offernig and initial data insights from the COVID-19 data.
Unraveling the Immune Response and Utility of a T-Cell Based Test in COVID-19
In this webinar, Harlan Robins, Co-founder and Chief Scientific Officer of Adaptive Biotechnologies, describes the efforts of the company along with researchers and collaborators around the world have taken to understand the SARS-CoV-2 virus and develop better diagnostics and therapuetics for COVID-19. Among these efforts is immunoSEQ® T-MAP™ COVID, which enables researchers to sudy the T-cell immune response to COVID-19. Learn about the current and future research applications of immunoSEQ T-MAP COVID.
Utilizing Immunosequencing in Immuno-Oncology and Immunotherapy Research
This webinar aims to provide an overview of Adaptive Biotechnologies’ immunoSEQ® Technology and cloud-based software, immunoSEQ® Analyzer. The webinar will cover functions of the Analyzer software and demonstrate how immunosequencing data can be incorporated into preclinical and clinical research with a focus on immuno-oncology and immunotherapy.
Exploring Repertoire Development and Dynamics with the immunoSEQ® Assay
Immunosequencing, the science of profiling T-cell receptors (TCRs) and B-cell receptors (BCRs), has been widely used to understand how the immune system changes in various disease states and how various treatment modalities impact immune responses. This webinar aims to provide an overview of Adaptive Biotechnologies' immunoSEQ® Technology and its applications in elucidating repertoire generation and dynamics.
Approaches to VDJ Sequencing
A variety of different V(D)J sequencing technologies have been used throughout the past few decades to profile the adaptive immune system. This webinar aims to provide an overview of those different approaches, how they have evolved, and a description of Adaptive Biotechnologies’ immunoSEQ® Technology and its utility for profiling large and diverse repertoires.
Immune Repertoire Data Analysis: From Sequencing Data to Insights
Recent advances in immunosequencing have allowed for accurate quantitation of the T- and B- cell immune repertoire, both in circulating cells and tumor infiltrating T cells. Immunosequencing has been used widely across biological disciplines to both assess changes over time and as a read-out of immune competence. Here we present an overview of Adaptive Biotechnologies' immunoSEQ® Technology and the use of robust statistical analyses across a range of biological fields including oncology and infectious disease.
COVID-19 T-Cell Data: Mapping Out SARS- CoV-2 Antigen & T-Cell Repertoires
In partnership with Microsoft, Adaptive Biotechnologies has created a comprehensive and detailed open access database, ImmuneCODE™, that provides COVID-19 data to accelerate ongoing efforts to develop better diagnostics, vaccines, and therapeutics for COVID-19. Here we will discuss the science behind the ImmuneCODE™ database presented in Nolan et al, some of the applications for which you can analyze the data, use of the immunoSEQ® T-MAP™ COVID offering, and initial data insights from the COVID-19 data described in Snyder et al.
Research Applications of the immunoSEQ Assay in Mouse Models
In this webinar, Dr. Richard DiPaolo, from Saint Louis University School of Medicine, will be discussing data generated in his laboratory that used the immunoSEQ® Assay along with various bioinformatic approaches to identify and track virus-specific T cells circulating in blood over long periods of time, determine the impact of immunotherapy on tumor-infiltrating T cells, and to quantitate the diversity of T cells specific for peptides from ZIKA virus.
Applications of Immunosequencing in Infectious Disease Research
This webinar will highlight infectious disease and vaccine research, and discuss published studies where immunoSEQ® Technology was leveraged. Topics will include repertoire properties associated with disease and vaccine responses, identifying antigen-specific clones, tracking clones over time and how repertoire and clone-level data can be integrated with clinical data to drive understanding and progress in the field.
Applications of immunoSEQ® in Transplantation Research
This webinar aims to provide an overview of Adaptive Biotechnologies' immunoSEQ® Technology and its applications in the field of transplantation research including applications in hemopoietic stem cell transplant (HSCT), graft-versus-host disease (GVHD), solid organ transplant, and immune reconstitution.
Applications of immunoSEQ® in Vaccine Research
This webinar aims to provide an overview of Adaptive Biotechnologies’ immunoSEQ® Technology and its applications in the field vaccine research. Viewers will learn about the utility of immunosequencing in general vaccine research and how immunoSEQ can be applied to vaccine applications in both infectious disease and cancer settings.
Utilizing the immunoSEQ® Assay in Clinical Trials
To date, there are no good preclinical models for HPV disease. Dr. Connie Trimble’s lab has developed methods to query the cervical mucosal microenvironment at a molecular level, in very small human tissue specimens. Dr. Trimble’s lab has designed and conducted a series of early phase, investigator-initiated clinical trials testing immunotherapies to treat incipient malignancies caused by HPV. Insights gained from longitudinal subject-matched tissue specimens have informed the design and choice of vaccine for each subsequent clinical trial. Data derived from longitudinal, prospectively-obtained, subject-matched specimens obtained from their protocol participants will be discussed.
From Bench to Biomarker: Applications of immunoSEQ Assay Across the Clinical Development Pipeline
Adaptive Biotechnologies’ quantitative immunoSEQ® Technology has the ability to answer early, preclinical questions such as those around drug candidate selection, dosing and effective drug combinations. As a therapeutic pipeline matures to the clinical trial stage, the immunoSEQ Assay can also help confirm drug safety and efficacy, establish biomarker endpoints, optimize patient selection, predict response to therapy and monitor for adverse events. This webinar will use real-world data to demonstrate how immunosequencing can be leveraged at various points in the drug development and clinical trial process to improve the development of new therapies for patients.
COVID-19 and the Immune System
An overview of publications featuring the immunoSEQ® Technology
- Discover the cutting-edge research on the t cell response to SARS-CoV-2 infection, how this compares to the antibody response, and correlations with disease severity.
- Read a breakdown of how various COVID-19 testing methods work, including RT-PCR, antibody-based, and T-cell based detection methods.
- See how Adaptive’s immunoSEQ® T-MAP™ COVID allows researchers to monitor the immunologic response to SARS-CoV-2 in vaccine development.
- Explore the impact of COVID-19 research in other disease contexts, including autoimmune diseases and oncology.
- Understand how the immunoSEQ® Technology and Adaptive’s immunoSEQ® T-MAP™ COVID can help further our understanding of COVID-19 exposure and immunity.