A role for autoimmunity in Parkinson’s Disease
In this webinar, you will discover:
- An overview of the immunoSEQ® Technology and how its quantitative nature enables accurate identification of disease-associated TCRB clones in response to antigen stimulation;
- How to confidently compare individual repertoires to identify public and private clones;
- Applications of immunosequencing to understand the role of T cells in Parkinson’s disease;
- How immunosequencing can be used to understand the immunological mechanisms underlying disease pathogenesis and progression in Parkinson’s disease and can potentially inform the development of immunotherapeutics and detection and disease tracking in research.
Immunosequencing, the science of profiling T- and B-cell receptors, has been widely used to understand how the adaptive immune system changes in various disease states and how different treatment modalities impact immune responses.
In this webinar, Dr. Nate Polaske provides a brief overview of immunosequencing with Adaptive Biotechnologies’ immunoSEQ® Technology.
Dr. Cecilia Lindstamn Arlehamn discusses her recent publication in Scientific Reports that utilized the immunoSEQ Assay. Here immunosequencing was used to explore the breadth and depth of the alpha-syn-specific TCRB repertoire in Parkinson’s disease patients to identify public clones that could inform and advance the development of novel Parkinson’s disease immunotherapeutics and diagnostics for early detection and disease monitoring in research.
For Research Use Only. Not for use in diagnostic procedures.
Cecilia Lindestam Arlehamn, PhD
La Jolla Institute for Immunology
Nathan Polaske, PhD
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